| Test Name: |
MYOSITIS SPECIFIC ANTIBODY EVALUATION, SERUM |
| Test Code: |
2194739 |
| Alias: |
LAB15984
MSAES
|
| CPT Code(s): |
86255 x 10
82397
86235
*84182 (if appropriate)
*86256 (if appropriate)
|
| Preferred Specimen: |
2.5 mL serum |
| Container: |
SST |
| Alternate Container: |
Red Top |
| Minimum Volume: |
1.5 mL |
| Collection Instructions: |
Allow specimen to completely clot. Centrifuge for 15 minutes when specimen is clotted or within 2 hours of collection. |
| Transport Temperature: |
Refrigerated |
| Stability: |
Refrigerated: 21 days Frozen: 21 days |
| Rejection Criteria: |
Gross hemolysis
Gross lipemia
Gross icterus
Heat-Treated |
| Limitations: |
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration. |
| Additional Information: |
* If the indirect immunofluorescence assay (IFA) pattern suggests signal recognition particle (SRP) antibody, then the SRP IFA titer and SRP54 immunoblot will be performed at an additional charge. |
| Schedule: |
Set up: Varies
Report Available: 4-8 days |
| Method: |
EJS, MDA5S, MI2S, NXP2S, OJS, PL12S, PL7S, SAE1S, TIFGS: Bead-Based Multi-Analyte Immunoassay
JO1: Multiplex Flow Immunoassay (MFI)
SRPIS, SRPTS: Indirect Immunofluorescence Assay (IFA)
HMGCR: Chemiluminescence Immunoassay (CIA)
SRPBS: Immunoblot (IB) MYSI: Technical Interpretation |
| Performing Lab: |
Mayo Clinic Dept of Lab Med & Pathology #MSAES |
| Clinical Significance: |
Useful for:
Accurately diagnosing, classifying, and managing idiopathic inflammatory myopathies (IIM) by identifying subtype-specific biomarkers that guide prognosis and treatment
Enabling early detection of IIM, particularly in atypical or severe cases, and reducing diagnostic uncertainty for personalized care |
| Use: |
Updated: 11/18/2025 |
| Reference Ranges: |
Myositis Specific Antibody Evaluation, Serum Test Information |
|
The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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| Test Type: |
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