| Test Name: |
BETA-2-MICROGLOBULIN, SERUM |
| Test Code: |
2198021 |
| Alias: |
852
B2 Microglobulin
LAB49
|
| CPT Code(s): |
82232
|
| Preferred Specimen: |
1.0 mL serum |
| Container: |
SST (gold) |
| Minimum Volume: |
0.5 mL serum |
| Collection Instructions: |
Allow specimen to completely clot. Centrifuge for 15 minutes. |
| Transport Temperature: |
Refrigerated |
| Stability: |
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days |
| Rejection Criteria: |
|
| Schedule: |
Set up: Mon-Sat; Report available: 1-2 days |
| Method: |
Immunoturbidometric |
| Performing Lab: |
Quest Diagnostics, Wood Dale; #852
|
| Clinical Significance: |
Beta-2-microglobulin normally passes through the glomerulus into the proximal tubule where much of it is reabsorbed. Serum levels are therefore an index of glomerular function. When impaired, serum levels rise in inverse ratio to glomerular filtration rate. Increased amounts of beta-2-microglobulin are excreted in several renal disorders, e.g., Balkan nephropathy, heavy metal poisoning and renal tubular disease due to therapeutic agents. Serial levels of beta-2-microglobulin in serum and urine are used to evaluate transplant viability and anticipate rejection. Following a successful graft, serum levels decline toward normal. Increasing serum levels provide an early sign of rejection. Elevated levels are also noted in lymphproliferative disorders, neoplasms (malignant and benign), inflammatory disease, and autoimmune diseases such as systemic lupus erythematosus (SLE) and Sjögren's disease. |
| Use: |
Updated 1/31/2025 |
| Reference Ranges: |
<18 Years Not established
Adults ≤2.51 mg/L |
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The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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| Test Type: |
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