| Test Name: |
LUPUS ANTICOAGULANT EVALUATION PANEL |
| Test Code: |
2186654 |
| Alias: |
LAB2214
|
| CPT Code(s): |
85613
85610
85670
85730
85613
85730
85730
|
| Test Includes: |
PT/INR, Thrombin Time, dRVVT Screen, dRVVT Confirm, SCT Confirm |
| Preferred Specimen: |
4.0 mL plasma |
| Container: |
3 - Sodium Citrates (lt blue) |
| Minimum Volume: |
2 - full Sodium Citrates (lt blue) |
| Collection Instructions: |
Tubes must be filled to completion to ensure a proper blood to anticoagulant ratio. Mix tubes gently by inverting 5-10 times immediately after filling. Centrifuge for 15 minutes within 1 hour of collection. Using a plastic pipette, remove plasma taking care to avoid the WBC/platelet buffy layer and transfer plasma into a properly labeled transfer tube. Centrifuge the transferred plasma a second time and transfer the platelet poor plasma into a new properly labeled purple frozen transport tube. Label tube as "platelet poor". Freeze immediately.
|
| Transport Temperature: |
Plasma: Frozen
Whole Blood - If testing will be performed within 4 hours: Room temperature |
| Stability: |
Frozen: 14 days
Room Temperature: 4 hours |
| Rejection Criteria: |
Refrigerated or room temperature plasma
Lipemia
Turbid sample
Hemolysis |
| Limitations: |
If the patient's hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted.
Icteric (Bilirubin > 13 mg/dL) and hemolyzed (Hemoglobin > 125 mg/dL) specimens may give false results. |
| Additional Information: |
It is preferable for samples to be obtained prior to, or in the absence of, anticoagulant therapy as this may interfere with the assay. Caution should be exercised in interpretation of the results of tests performed close to a thromboembolic event. |
| Schedule: |
Set up: Mon-Fri; Results in 1-3 days |
| Method: |
Silica Clotting Time (SCT) and dRVVT screen; mixing study if screening tests are prolonged; confirmation if the mixing studies do not correct |
| Clinical Significance: |
Lupus anticoagulants are nonspecific antibodies that extend the clotting time of phospholipid-dependent clotting assays such as the aPTT. Unlike specific factor antibodies, LA are usually associated with venous thrombosis, pulmonary embolism, arterial thrombosis, and recurrent fetal loss. |
| Reference Ranges: |
DRVVT Test Ratio (TR) is ≤ 1.19 (Negative)
SCT Test Ratio (TR) is ≤ 1.16 (Negative) |
|
The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
|
| Test Type: |
|