Health Lab

Test Name:

VANCOMYCIN, TROUGH

Test Code:

2120279

Alias:

LAB39
Vancocin

CPT Code(s):

80202

Preferred Specimen:

1.0 mL serum

Container:

Plain Red (no gel)

Alternate Container:

Minimum Volume:

0.3 mL serum
This volume does not allow for repeat testing.

Collection Instructions:

Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes. Transfer serum to a plastic transfer tube, and specify "serum" on the transfer tube label.

Transport Temperature:

Refrigerated

Stability:

Refrigerated: 4 days (capped)

Frozen: 12 months (capped)

Rejection Criteria:

Specimens collected in SST (gel separator) tubes are not acceptable for testing.

Limitations:

Additional Information:

Interference may occur with serum samples with patients diagnosed as having plasma cell dyscrasias and lymphoreticular malignancy associated with immunoglobulin synthesis, such as multiple myeloma, Waldenström's macroglobulinemia, and heavy chain disease. Results for these patients are typically suppressed.

Schedule:

Set up Daily; Results in 24-48 hours

Method:

EMIT

Clinical Significance:

Vancomycin is a glycopeptide antibiotic. It is primarily used in the treatment of infections due to β-lactam or methronidazole-resistant gram positive cocci and bacilli. It may be used prophylactically in some patients who are at risk for endocarditis or when methicillin-resistant staphylococcus aureus or staphylococcus epidermidis is at risk. Since individual patients exhibit a high degree of variability in absorption and metabolism of vancomycin, therapeutic monitoring is recommended in certain patients. The major toxic reactions include “red-man syndrome”, nephrotoxicity, and ototoxicity when very high levels of the drug are present in the circulation.

Critical Values:

>20 ug/mL

Use:

Updated 02/16/22

Reference Ranges:

Trough serum values: 5.0-10.0 μg/mL

Reference Range Table

Result	Units	Gender	Age	Range
Vancomycin, Trough	mcg/mL	Both	0 Year - 999 Year	10.0-20.0

The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.