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Health Lab Test Code Build Information
Test Name:	STREPTOCOCCUS PNEUMONIAE IgG ANTIBODY PANEL (14 SEROTYPES)
Test Code:	2195567
Alias:	19564 LAB778 Streptococcus pneumoniae IgG Antibody Panel (14 Serotypes)
CPT Code(s):	86581
Test Includes:	Serotypes 1, 3, 4, 5, 8, 9 (9N), 12 (12F), 14, 19 (19F), 23 (23F), 26 (6B), 51 (7F), 56 (18C), 68 (9V)
Preferred Specimen:	0.5 mL serum
Container:	SST (gold)
Minimum Volume:	0.25 mL serum
Collection Instructions:	Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes as soon as the specimen is clotted. If you are interested in PRE and POST vaccination testing, please follow these instructions: PRE and POST samples should be tested together on the same run to avoid variation in results caused by lot to lot and inter assay variation. It is recommended that two PRE tubes be drawn. Save one PRE serum frozen. The other can be sent to determine the need to vaccinate. If patient already has protective values, there is no need to revaccinate and test a POST sample. If PRE results do not show protective values, send the saved PRE sample together with the POST vaccination sample.
Transport Temperature:	Room temperature
Stability:	Room temperature: 7 days Refrigerated: 14 days Frozen: 90 days
Limitations:	This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Schedule:	Set up: Mon-Fri; Report available: 3-5 days
Method:	Multi-Analyte Immunodetection (MAID)
Performing Lab:	Quest Diagnostics, Valencia >SJC; #19564
Clinical Significance:	Streptococcus pneumoniae Antibody (IgG) (14 Serotypes), MAID - Responses to pneumococcal conjugate vaccines are demonstrated by 2-to 4-fold increases in type-specific IgG levels.
Use:	Updated: 10/24/2025

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	The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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