Test Name: PSEUDOCHOLINESTERASE, TOTAL, SERUM
Test Code: 2198312
Alias: LAB9126
PCHE1
CPT Code(s): 82480  
Preferred Specimen: 0.5 mL serum
Container: SST
Alternate Container: Red Top
Minimum Volume: 0.25 mL
Collection Instructions: Allow specimen to completely clot. Centrifuge for 15 minutes when specimen is clotted or within 2 hours of collection.
Transport Temperature: Refrigerated
Stability:
Room temperature: 24 hours
Refrigerated: 14 days
Frozen: 365 days
Limitations: This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
Schedule:
Set up: Monday through Friday
Report Available: 1-4 days
Method: Colorimetric Assay
Performing Lab: Mayo Clinic Dept of Lab Med & Pathology #PCHE1
Clinical Significance:
Useful for:
Monitoring exposure to organophosphorus insecticides and herbicides

Monitoring patients with liver disease, particularly those undergoing liver transplantation

Identifying patients who are homozygous or heterozygous for an atypical gene and have low levels of pseudocholinesterase

This test is not useful for the differential diagnosis of jaundice.
Use: Updated: 01/28/2025
Reference Ranges:
Males:
5320-12,920 U/L

Females:
0-15 years: 5320-12,920 U/L
16-39 years: 4260-11,250 U/L
40-41 years: 5320-12,920 U/L
> or =42 years: 5320-12,920 U/L

Note: Females aged 18-41 years who are pregnant or taking hormonal contraceptives, the reference interval is 3650-9120 U/L.

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The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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