Test Name: |
NEURON SPECIFIC ENOLASE (NSE) |
Test Code: |
2192848 |
Alias: |
LAB19906
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CPT Code(s): |
86316
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Preferred Specimen: |
1 mL serum |
Container: |
SST (gold) |
Minimum Volume: |
0.2 mL serum |
Collection Instructions: |
Allow specimen to completely clot (this can take up to 60 minutes). Centrifuge for 15 minutes |
Transport Temperature: |
Room temperature |
Stability: |
Room temperature: 7 days Refrigerated: 14 days Frozen: 30 days |
Limitations: |
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. |
Schedule: |
Set up: Tues, Thurs, Sat; Report available: 1-4 days |
Method: |
Immunoassay (IA) |
Performing Lab: |
Quest Diagnostics, Valencia; #34476 |
Clinical Significance: |
Elevated levels of serum NSE are reported in patients with small cell carcinomas primarily of lung origin. Patients with neuroblastomas may also have high levels of NSE. Serum NSE can be used to monitor recurrence or progression of tumor in these cancer patients. Daily serial monitoring of serum NSE may also be used in comatose patients to assess neuronal damage. High NSE levels in comatose patients at 24hr and 48hr post cardio-pulmonary resuscitation have been associated with poor outcome. Hemolysis can cause false positive results. |
Use: |
Updated 02/16/22 |
Reference Ranges: |
<10.8 ng/mL |
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The CPT codes included in this publication are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients; however, correct coding often varies from one carrier to another, and HealthLab may bill specific carriers using codes other than those shown. Clients who bill for services should verify the code(s) with the applicable payor to confirm that their use is appropriate in each case.
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